Localized chemical changes in heart tissue during chronic cardiac Chagas Disease
This study analizes the heart tissue of chronically T. cruzi-infected and uninfected mice, to understand the impact of infection on the tissue metabolome.
04/11/2021
The results show differencies amongst regions according to its parasite burden. This identification gives insight into severe cardiac symptom development in 30 % of patients during the chronic stage.
Analyzing this changes brings an approach to understand cardiac symptom better and also shapes a framework for novel Chagas Disease treatment.
Read the entire study by clicking on PLOS.
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